Programme [12/10/2018]

Programme & Abstracts book [23/10/2018]

• Tuesday
• Wednesday
• Thursday
• Friday
• Posters

• Tuesday, 18 September
  11:00-13:00	Registration
  13:30-13:50	Opening & Welcome     [Aula Magna] Eugenio Gaudio (Rector, Sapienza University of Rome) Gennaro Ciliberto (FISV President)
  13:50-14:00	Tribute to Luigi Luca Cavalli-Sforza: a Pioneering Geneticist     [Aula Magna] Lucio Luzzatto (Muhimbili University of Health and Allied Sciences, Tanzania)
  14:00-15:00	The EMBO Keynote Lecture     [Aula Magna] FISV Lecture Riccardo Cortese Chair: Valeria Poli (Turin) Wolf Reik (The Babraham Institute and University of Cambridge, Cambridge, UK) Single cell epigenome landscape of development and ageing
  15:00-17:00	Plenary Symposium     [Aula Magna] The Circadian Clock. A Living Organism’s Best Friend in a Spinning World Chairs: Alex Costa (Milan), Rodolfo Costa (Padua) Amita Sehgal (Howard Hughes Medical Institute and University of Pennsylvania, USA) How do clocks control behavior and physiology: insights from a small animal model Jay C. Dunlap (Geisel School of Medicine at Dartmouth, Hanover, NH, USA) The regulatory network governing global responses to changes in light and time Alex A. R. Webb (University of Cambridge, UK) Dynamic plasticity of circadian oscillators
  17:00-17:30	Coffee break     [Terrace]
  17:30-19:30	Round Table     [Aula Magna • This session will be in Italian] Which future for the smart biotechnologies Chair: Anna Meldolesi (Corriere della sera, CRISPeR Mania) Anna Cereseto (Università di Trento) Andrea Lenzi (Sapienza Università di Roma e CNBBSV) Massimo Losito (Ateneo Pontificio Regina Apostolorum, Roma) Michele Morgante (Università di Udine) Luigi Naldini (San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milano) Sandro Vitale (Istituto di Biologia e Biotecnologia Agraria, CNR, Milano)
  19:30-20:30	Welcome Cocktail     [Terrace]

   

• Wednesday, 19 September
  8:30-11:30	Short talks by participants (Session I)

  • PSI.1
  • PSI.2
  • PSI.3
  • PSI.4
  • PSI.5
  • PSI.6

  • 8:30-10:00

    Environmental Microbiology and Biotechnology     [Aula P1] Chairs: Duccio Cavalieri, Teresa Rinaldi Annamaria Bevivino (Rome) Environmental microbial signatures revealed by metagenomic analysis of the airways of cystic fibrosis patients Bruno Casciaro (Rome) Frog-skin esculentin-1a derived peptides against Pseudomonas aeruginosa keratitis: anti-biofilm activity and immobilization to soft contact lenses Simona Crognale (Rome) Exploitation of biological As(III)-oxidation in water treatment systems: potentialities and microbiome profiling in bioreactors Giovanni Bacci (Sesto Fiorentino, FI) Flying to Mars: the human microbiome under isolated conditions Francesca D'Angelo (Rome) Biotechnological exploitation of bacterial communication processes: from quorum sensing inhibition to the generation of synthetic cells interfacing with natural cells

    10:00-11:30

    Genetics of Microorganisms     [Aula P1] Chairs: Francesco Imperi, Renato Fani Sarah Hijazi (Rome) Hijacking bacterial iron metabolism using the transition metal gallium Alice Checcucci (Sesto Fiorentino, FI) Playing with the rhizobial Mega-Apps: creation and multi-omics characterization of a genomically hybrid strain in the nitrogen-fixing symbiotic bacterium Sinorhizobium meliloti Olivier Jousson (Trento) The role of Type VI Secretion System on the competitiveness of P. aeruginosa clinical isolates Paola Sperandeo (Milan) Characterization of an E. coli suppressor mutant that can survive and assemble a functional LPS transport machinery in the absence of the essential inner membrane-tethered LptC Alessandra Fortuna (Rome) DksA-dependent regulation of quorum sensing in Pseudomonas aeruginosa

  • 8:30-10:00

    Genomics, Proteomics and Systems Biology     [Aula C – Biochimica, 2° Floor] Chairs: Andrea Bellelli, Graziano Pesole Federico Martinelli (Palermo) Meta-analysis of RNA-seq data to gain insight into crop responses to environmental stresses Marco Russo (Bologna) Analyses of genomic R-loop maps induced by G-quadruplex ligands in human cancer cells Federica Zinghirino (Catania) VDAC (voltage dependent anion selective channel) promoters elements and their involvement in metabolic stress Elisa Margherita Maffioli (Milan) Nanostructured surfaces promote differentiation and maturation events in different cell types Marcello Manfredi (Alessandria) Integrating serum proteomics, metabolomics and lipidomics to study the effect of sport activity

  • 8:30-10:00

    Chromosome Biology, Cell Division and Cell Cycle     [Aula Montalenti – Genetica] Chair: Giulia Guarguaglini Valeria Palumbo (Rome) Morgana/CHP-1 is required for oogenesis and early embryonic divisions in Drosophila Patrizia Lavia (Rome) RANBP2: a nucleoporin with key roles in protein SUMOylation Ferdinando Di Cunto (Orbassano, TO) Citron kinase inactivation inhibits medulloblastoma progression by inducing apoptosis and cell senescence Patrizia Sarogni (Pisa) Cohesin over-expression promotes colorectal cancer development Veronica Ferrucci (Naples) A genotype/ phenotype correlation study to dissect the clinical features of the PRUNE-1 syndrome (#617481)

    10:00-11:30

    DNA Replication, Repair and Recombination     [Aula Montalenti – Genetica] Chairs: Antonio Musio, Ennio Prosperi Serena Montalbano (Parma) Identification of the biological target of new platinum, copper and nickel complexes Anita Palma (Rome) MUS81 endonuclease activity is regulated by CHK2 for replication forks rescue upon replication stress and BRCA2 depletion Antonella Porrazzo (Rome) Low doses of gamma irradiation render Drosophila melanogaster resistant to the DNA damage Elisa Palumbo (Padua) Identification of molecular biomarkers useful for predicting the likelihood of radiation-induced side effects in oncological patients undergoing radiotherapy Giulio Ticli (Pavia) Live cell imaging analysis of the influence of p21CDKN1A on PCNA-partners turnover at UV-induced DNA damage sites

  • 8:30-10:00

    Oncogenes and Tumor Suppressors     [Aula Magna] Chairs: Sara Cabodi, Miriam Martini Giulia Bon (Rome) HMGA1/E2F1 axis and NFkB pathways regulate LPS progression and trabectedin resistance Amani Bouzidi (Rome) Impact of the inhibition of the mitochondrial Serine hydroxymethyltransferase enzyme in mitochondrial respiration and cancer cell growth Viola Calabrò (Naples) Secreted YB-1 regulates NFkB signaling pathway in receiving cells Lidia Chellini (Rome) Regulation of ovarian cancer progression by IQGAP1 through endothelin-1 receptor signalling Silvia Soddu (Rome) The p53 mitotic centrosomal localization contributes to mitotic surveillance pathway

    10:00-11:30

    Cellular Stress, Apoptosis and Autophagy     [Aula Magna] Chairs: Daniela Barilà, Lucia Morbidelli Romina Burla (Rome) A new telomeric and ESCRT complex associated factor Andrea Guarino (Naples) YB-1 recruitment to stress granules in Zebrafish reveals a differential adaptive response Alberto Inga (Trento) An RBP complex containing DHX30 and PCBP2 operates translation control acting as gatekeeper for p53-dependent apoptosis Marialuisa Piccolo (Naples) Nucleolipidic-based Ru(III) nanosystems induce multiple cell death pathways activation in preclinical models of human breast cancer Gaetana Paolella (Fisciano, SA) Involvement of mitochondria and endoplasmic reticulum in stress response to the environmental pollutant 4-Nonylphenol in a human liver cell line

  • 8:30-10:00

    Transcriptional Mechanisms and Epigenetic Modifications     [Aula Giacomini – Botanica] Chairs: Giacomo Donati, Aymone Gurtner Michele Menotta (Urbino) ATM unconventional splicing modulation by glucocorticoids Veronica Ruta (Rome) Strategies to inhibit PRC2 methyltransferase activity in Arabidopsis seedlings Annalisa Roberti (Pavia) Epigenetic marks at satellite-free and satellite-based centromeres Elisa Coluzzi (Rome) How oxidative stress affects telomere structure and telomeric epigenetic modifications?

    10:00-11:30

    Non-coding RNA     [Aula Giacomini – Botanica] Chairs: Alessandro Fatica, Francesca Orso Silvia Biscarini (Rome) LncRNAs in motor neuron differentiation and physiopathology Neri Mercatelli (Rome) HULC/miR-186/Twist: a novel molecular axis in the resistance of Ewing Sarcoma to YK-4-279 Simone Detassis (Trento) An innovative technology for the direct detection of microRNAs in biofluids Giorgio Dieci (Parma) SINE-encoded ncRNA profiling unveils a new layer of epigenetic dysregulation in cancer Lidia Villanova (Rome) MiR-663 sustains NSCLC by inhibiting mitochondrial outer membrane permeabilization (MOMP) through PUMA/BBC3 and BTG2

  • 8:30-10:00

    Plant Nutrition and Biofortification     [Aula A – Fisiologia Generale] Chairs: Laura De Gara, Anita Zamboni Francesca Cardinale (Grugliasco, TO) Strigolactones effects on root acidification ability Sara Cimini (Rome) Lead exposure differentially affect growth, antioxidative network and nutrient uptake in metallicolous and non-metallicolous Zygophyllum fabago populations Flaviana Marzano (Bari) Scouting cross-kingdom transfer: effect of plant microRNA on the expression of human genes involved in cell proliferation Pasqualina Woodrow (Caserta) Tvv1 retrotransposon family is activated by seaweed extracts in Micro-Tom genome Sezen Yilmaz-Sarialtin (Ankara, Turkey) In vitro antioxidant and anti-inflammatory activities of some viola L. species in Turkey

    10:00-11:30

    Photosynthesis, Metabolism and Environmental Stress     [Aula A – Fisiologia Generale] Chairs: Cinzia Bertea, Nicola Tomasi Giulia Russo (Grugliasco, TO) Strigolactones and abiotic stress in plants: modulation of abscisic acid transport Cecilia Brunetti (Sesto Fiorentino, FI) Abscisic acid dynamics in leaves, shoot and roots of Populus nigra exposed to drought: relationships with water relations and carbohydrate status Libero Gurrieri (Bologna) Rearrangements in carbon metabolism under osmotic stress: from central metabolism to stress response Davide Marzi (Rome) COP1 mediates light-controlled stamen growth in Arabidopsis thaliana Alberta Pinnola (Verona) Archeology of stress-resistance genes: a novel strategy to improve photosynthesis and productivity in crops

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  11:30-12:00	Coffee break     [Terrace]
  12:00-13:00	Plenary Lecture     [Aula Magna] Chair: Omar Rota-Stabelli (Trento) Alexei Maklakov (University of East Anglia, Norwich, UK) Why do we age: disposable soma of functional trade-offs?
  13:00-13:15	SARTORIUS Short Talk     [Aula Magna] T. Claudio Bencivenga (Milan) IncuCyte® S3: live-cell analysis system
  13:15-14:30	Lunch time and Posters viewing (Session I)
  14:30-16:30	Plenary Symposium     [Aula Magna] Oxidative Stress, Protein Damage and Repair: Implications in Health and Disease Chair: Alessandra Polissi (Milan), Roberto Sitia (Milan) Frédéric Barras (Institut Pasteur, Paris, France) Protein homeostasis control: fighting ROS damages by repairing oxidized proteins Roberto Sitia (Università Vita-Salute San Raffaele, Milan) Tuning redox signaling in and between cells Alessandro Giuffrè (CNR-IBPM, Rome) Energy, redox status and gasotransmitters: poisons at work! Giovanna De Chiara (CNR, Rome) Recurrent Herpes Simplex Virus -1 (HSV-1) infection causes neurodegenerative signs and cognitive deficits in mice. Role of protein oxidation
  16:30-17:00	Coffee break     [Terrace]
  17:00-19:00	Parallel Symposia 1. Emergence and Spread of Archaic and Modern Humans: News from Bones and Genomes     [Aula P1] Chairs: Antonio Torroni (Pavia), Luca Sineo (Palermo) Giorgio Manzi (Sapienza University of Rome) The evolution of the genus Homo has been driven by a series of geographical dispersals Robert Foley (University of Cambridge, UK) Evolution of Homo sapiens in Africa: integrating genes, fossils and behaviour Carles Lalueza-Fox (CSIC-University Pompeu Fabra, Barcelona, Spain) Genomics of the bell beaker phenomenon and the transformation of Western Europe Cristian Capelli (University of Oxford, UK) Recent, ancient and archaic genomic signatures in the Italian population 2. Genetic and Epigenetic Mechanisms Regulating Transgenerational Inheritance     [Aula Magna] Chairs: Michele Morgante (Udine), Antonella Russo (Padua) Marco Barchi (University of Rome Tor Vergata) Molecular mechanisms underlying X-Y chromosomes segregation errors during meiosis EMBO Young Investigator Lecture Nicola Iovino (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) Epigenetic inheritance through the germline in Drosophila James Hackett (EMBL, Monterotondo, Rome) Genetic and epigenetic regulation of the mammalian germline EMBO Young Investigator Lecture Isabel Bäurle (University of Potsdam, Germany) Chromatin regulation of heat stress memory in plants 3. Proteins as Drug Target and Drugs, and Protein Degradation as a Therapeutic Strategy     [Aula Giacomini – Botanica] Chairs: Alberto Boffi (Rome), Andrea Mozzarelli (Parma) Giuseppe Zanotti (University of Padua) Structural determination of proteins of Helicobacter pylori relevant for bacterial survival and pathogenicity Antonella Isacchi (Nerviano Medical Sciences, Milan) Kinases as drug targets: state of the art and future perspectives Cecilia Weigelt (Biotech Research & Product Development, Chiesi Group, Lidingo, Sweden) The CMC and biological development path of an enzyme replacement therapeutic drug - from idea to EMA approval Alessio Ciulli (University of Dundee, Scotland, UK) Drug design for targeted protein degradation 4. Crossing Biological Barriers, in Health and Disease     [Aula Montalenti – Genetica] Chairs: Massimo Masserini (Milan), Vito De Pinto (Catania) Francesca Re (University of Milano-Bicocca) Modeling the blood-brain barrier (BBB) in healthy and diseased states Sara Nicoli (University of Parma) Innovative strategies to overcome ocular barriers Valeria Dall’Asta (University of Parma) Cationic amino acid transport: physiology and pathology Krisztina Herédi-Szabó (SOLVO Biotechnology, Budaörs, Hungary) Challenges and opportunities to develop drugs traversing biological barriers
  19:00-21:00	Societies' time AGI     [Aula Magna] 19:00 Premio AGI "Ferruccio Ritossa" 2018 e presentazione del lavoro premiato 19:20 Premio Dottorato AGI/Zanichelli 2018 e presentazione del lavoro premiato 19:40 Assemblea dei Soci AGI SIBV     [Aula Montalenti – Genetica] Premi 2018: - SIBV Seed Grants - Giovani Biologi Vegetali Assemblea Sociale SIMAG     [Aula Giacomini – Botanica] Assemblea dei soci

• Thursday, 20 September
  8:30-11:30	Short talks by participants (Session II)

  • PSII.1
  • PSII.2
  • PSII.3
  • PSII.4
  • PSII.5
  • PSII.6

  • 8:30-10:00

    Development, Differentiation and Ageing     [Aula Sergi – Antropologia, 1° Floor] Chairs: Daniele Condorelli, Fulvio Della Ragione Adriana Borriello (Naples) Studies on cancer-associated CDKN1B mutations: unravelling a novel mechanism for tumor suppressor loss of function Marina Bruno (Florence) Role of sphingosine 1-phosphate signaling axis in the differentiation of epithelial cochlear progenitors Roberta Cascella (Florence) The mechanism of neuronal toxicity by oligomers and fibrils of a-synuclein Stefania Martucciello (Fisciano, SA) Tbx1 interacts genetically with Vegfr3 to regulate lymphangiogenesis in mice Rebecca Piccarducci (Pisa) Influence of APOε polymorphism and physical activity on the well-being of erythrocytes: antioxidant capability and cellular membrane assessment

    10:00-11:30

    Stem Cells, iPS, Cancer Stem Cells     [Aula Sergi – Antropologia, 1° Floor] Chairs: Gianni Cuda, Gabriele Stocco Maria Giovanna Garone (Rome) Development of new cranial motor neuron differentiation protocol from human iPS cells carrying ALS mutations Chiara Giacomelli (Pisa) New insights on the human bone-marrow and gingival mesenchymal stem cell responses to senescence induction Giusj Pugliese (Rome) Generation of an iPSC model to investigate replicative stress as the possible molecular mechanism underlying Schimke immune-osseous dysplasia Alessandro Rosa (Rome) Dysregulation of RNA metabolism in iPSC-derived FUS mutant human motor neurons, an in vitro model system for Amyotophic Lateral Sclerosis Federico Salaris (Rome) Transcriptome and proteome analysis of FXS patient-derived iPSC lines to investigate FMRP role and its interactors during neural development

  • 8:30-10:00

    Metabolism and its Regulation in Health and Diseases     [Aula C – Biochimica, 2° Floor] Chairs: Mauro Magnani, Luigi Palmieri Giulia Guiducci (Rome) Beyond intermediary metabolism: characterization of the moonlighting function of human serine hydroxymethyltransferase Alessio Menga (Bari) Blockade of glutamine synthetase enhances inflammatory response in microglial cells Vito Porcelli (Bari) Molecular identification and functional characterization of a novel glutamate transporter in yeast and plant mitochondria Karim Zuhra (Rome) Synthesis and breakdown of H2S, the third gasotransmitter Gianluca Mattei (Florence) Metabolism in breast cancer: a systems biology approach

  • 8:30-10:00

    Human Genetics and Genomic Diversity     [Aula Montalenti – Genetica] Chairs: Alessandro Achilli, Luca Pagani Michela Leonardi (Cambridge, UK) Human genetic diversity and the effects of subsistence strategies Angelica Macauda (Pisa) Inherited variation in the xenobiotic transporter patwhay and survival of multiple myeloma (MM) patients: an IMMEnSE study Manuel Gentiluomo (Pisa) A Mendelian randomization approach to predict the risk to develop pancreatic ductal adenocarcinoma Marco Capodiferro (Pavia) Exploring the genetic history of Panamanians through ancient genomes Linda Ongaro (Tartu, Estonia) The european heritage of american populations

    10:00-11:30

    Evolutionary Biology     [Aula Montalenti – Genetica] Chairs: Giorgio Manzi, Marco Oliverio Valeria Russini (Rome) A biogeographic analysis of loss of planktotrophy in caenogastropod molluscs (Gastropoda, Nassariidae) Omar Rota Stabelli (San Michele all'Adige, TN) The genome of Drosophila subpulchrella helps polarising the evolution of pest traits in its sister species Drosophila suzukii Roberto Feuda (Bristol, UK) A common regulatory neurogenic toolkit in Bilateria Costantino Buzi (Rome) On the shoulder of the past. The scapula of the Neanderthal from Altamura, Italy

  • 8:30-10:00

    Neurobiology and Neuropharmacology     [Aula A – Fisiologia Generale] Chairs: Giulia Piaggio, Giorgio Racagni Carlo Brighi (Rome) Modeling Fragile X syndrome with iPSC-derived neurons as a purpose of deciphering the molecular mechanisms and the neurobiological phenotypes associated with the pathology Anna Maria Lucianò (Rome) M2 muscarinic receptors show inhibitory effects on drug resistance in human neuroblastoma cells Claudia Colussi (Rome) Nitro-oxidative stress dependent Nup153 alteration affects neural stem cell function in a mouse model of Alzheimer’s disease Serena Faggiano (Parma) Human serine racemase, a drug target for neuropathologies Ciro Iaccarino (Sassari) Role of LRRK2 in the regulation of dopamine receptor trafficking

    10:00-11:30

    Nutrition Biochemistry     [Aula A – Fisiologia Generale] Chairs: Francesco Bonomi, Silvana Hrelia Paola Antonia Corsetto (Milan) Nutrient deprivation alters lipid phenotype in triple-negative breast cancer Simone Luti (Florence) Investigating the nutraceutical properties of peptides extracted from Tuscany sourdoughs Laura Giusti (Pisa) A proteomic approach to study the neuroprotective effect of oleocanthal in SH-SY5Y cells Stefania Iametti (Milan) Structure-dependent biological activities of food-related stilbene derivatives isomers Pasquale Marrazzo (Rimini) Enhancing stem cell functionality through antioxidant supplementation

  • 8:30-10:00

    Immunology and Host-Pathogen Interaction     [Aula Magna] Chairs: Fiorentina Ascenzioni, Paolo Visca Duccio Cavalieri (Sesto Fiorentino, FI) Strain level analysis of intestinal fungi and immune mediated host-yeast interaction Marta Kinga Lemieszek (Lublin, Poland) Beneficial effect of cathelicidin on treatment of hypersensitivity pneumonitis induced by Pantoea agglomerans – in vivo studies Maria Luisa Mangoni (Rome) How to control Pseudomonas aeruginosa-induced pneumonia? A lesson from derivatives of the amphibian skin peptide esculentin-1a Luca Cavinato (Rome) Escaping the oxidative burst: dual role of the P. aeruginosa superoxide dismutases Federica Runci (Rome) The contribution of iron uptake to Acinetobacter baumannii pathogenicity

    10:00-11:30

    Plant Development and Disease     [Aula Magna] Chairs: Franco Faoro, Michela Zottini Alex Costa (Milan) Looking for aminoacid-gated calcium channels in plants: functional, biochemical and structural characterization of one GLR isoform Cristina Ruberti (Muenster, Germany) Fine-tuning the unfolded protein response in plants Anna Fiorillo (Rome) Biochemical characterization of Salt tolerance-related protein (STRP): a new protein involved in cold stress in A. thaliana Federica Locci (Rome) Oxidation of Damage-Associated Molecular Patterns as a homeostatic mechanism in plant immunity and development Vincenzo Lionetti (Rome) Pectin methylesterases in plant immunity: activators or susceptibility factors?

  • 8:30-10:00

    Biotransformations     [Aula Giacomini – Botanica] Chairs: Loredano Pollegioni, Raffaele Porta Paola Branduardi (Milan) Optimizing the biotransformation of residual biomasses by ameliorating the effectiveness of cell factories Mohammed Sabbah (Naples) Innovative chitosan-based biodegradable plastics as food coating and wrapping Valeria Vecchi (Verona) Identification of two novel hemicellulosolytic enzymes from the hyperthermophilic bacterium Thermotoga neapolitana and their exploitation for lignocellulose degradation Andrea Franzetti (Milan) Removal and biodegradation of air pollutants by plant-bacteria interactions in urban areas Sara Ragucci (Caserta) Purification and characterization of a novel peroxidase from seeds of Araujia sericifera Brot

    10:00-11:30

    Glycoconjugates     [Aula Giacomini – Botanica] Chairs: Alberto Passi, Eugenia Schininà Livia Cabitta (Milan) Identification of the antigen recognized by rHIgM22, a remyelination-promoting human monoclonal antibody and his effect on glial cells Ilaria Caon (Varese) The long non coding RNA HAS2-AS1 regulates breast cancer cells aggressiveness acting as a competing endogenous RNA Elena Caravà (Varese) Role of TNFα on endothelial glycocalyx Michela Pucci (Bologna) Glycosylation in colorectal cancer: role of B4GALNTII and Sialyl Lewis x antigen

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  11:30-12:00	Coffee break     [Terrace]
  12:00-13:00	Plenary Lecture     [Aula Magna] Chair: Mario Pezzotti (Verona) Luis Herrera Estrella (LANGEBIO, Mexico) Genetically modified plants: past, present and future
  13:00-13:15	SENECO Short Talk     [Aula Magna • this talk will be in Italian] Ettore Senes (Milan) Ultrasound-assisted emerging technologies for applied and basic research
  13:15-14:30	Lunch time and Posters viewing (Session II)
  14:30-16:30	Plenary Symposium     [Aula Magna] Life is Also a Matter of Taste and Smell Chairs: Roberto Barale (Pisa), Guglielmina Nadia Ranzani (Pavia) Wolfgang Meyerhof (Saarland University, Homburg, Germany) Different tongues for different people? - Genetics of bitter taste receptors and perceptual differences in individuals and the population Catia Sternini (UCLA, Los Angeles, CA, USA) Gut bitter taste receptors as sensors of luminal content Paolo Gasparini (University of Trieste) Genes and food preferences and their role in personal choices, lifestyle and health Darren Logan (Wellcome Trust Sanger Institute, Cambridge, UK) Do you smell what I smell? The genetics of olfaction
  16:30-17:00	Coffee break     [Terrace]
  17:00-19:00	Parallel Symposia 1. RNA Biology     [Aula A – Fisiologia Generale] Chairs: Irene Bozzoni (Rome), Salvatore Oliviero (Turin) Danny Incarnato (IIGM, Turin) Dissecting the RNA structurome to decipher in vivo RNA folding dynamics Gian Gaetano Tartaglia (Centre for Genomic Regulation and ICREA, Barcelona, Spain) Aggregation, neurodegeneration and RNA networks Julie Martone (Sapienza University of Rome) Lnc-049, a cytoplasmiclLong non-coding RNA involved in skeletal muscle differentiation 2. Inflammation and Disease     [Aula Magna] Chairs: Carlo Riccardi (Perugia), Paolo Pinton (Ferrara) Cecilia Garlanda (Humanitas University, Milan) IL-1R8, a negative regulator of inflammation and checkpoint molecule Francesco Di Virgilio (University of Ferrara) ATP: the quintessential DAMP Maria Lina Bernardini (Sapienza University of Rome) PAMPs: linking bacterial recognition and inflammatory response Stefano Bruscoli (University of Perugia) Glucocorticoid and B cell functions: role of Glucocorticoid-Induced Leucine Zipper (GILZ) 3. Carbon Cycle and Climate Change: the Future     [Aula Montalenti – Genetica] Chairs: Luca Espen (Milan), Sergio Esposito (Naples) Maria De Nobili (University of Udine) Soil, the second active planet scale interface: effects and perspectives of climate change Nick Ostle (Lancaster University, UK) Climate change and soil biotic carbon cycling Mauro Centritto (IVALSA, CNR, Florence) Evolution of stomatal and mesophyll conductance: implications for carbon and water exchange in drylands Rémi Lemoine (CNRS and University of Poitiers, France) Flux of carbon from leaves to roots in plants under environmental stress
  21:00	Social dinner     [Ristorante La Limonaia]

   

• Friday, 21 September
  8:30-10:30	Plenary Symposium     [Aula Magna] Farming for Pharming: Plants as Biofactories (in the Production of Vaccines, Antibiotics, Anticancer) Chairs: Marcello Donini (Rome), Franco Faoro (Milan) Emanuela Noris (CNR, Turin) Transient expression of anticancer and antiviral antigens in plants Julian K-C. Ma (St. George’s, University of London, UK) Molecular pharming in tobacco to provide antibody based solutions for global health Selene Baschieri (ENEA Centro Ricerca Casaccia, Rome) Plant-derived vaccines and smart drugs Linda Avesani (University of Verona) Plant-made nanomaterials for diagnosis and therapy
  10:30-11:30	Plenary Lecture     [Aula Magna] Chair: Bianca Colonna (Rome) Josep Casadesús (University of Seville, Spain) Waddington's landscapes in the microbial world
  11:30-11:45	SEQUENTIA BIOTECH Short Talk     [Aula Magna] Walter Sanseverino (Barcelona, Spain) When computer science meets life science: novel bioinformatics approaches to improve NGS data interpretation
  11:45-12:00	Coffee break     [Terrace]
  12:00-14:00	Plenary Symposium     [Aula Magna] Regulatory Network Dynamics: from Interaction to Function Chairs: Matteo Barberis (Amsterdam, The Netherlands), Pier Luigi Martelli (Bologna) FEBS National Lecturer - Luis Serrano Pubul (Centre for Genomic Regulation, Barcelona, Spain) Comprehensive systems analysis of the transcriptome and its regulation of a genome reduced bacterium Matteo Barberis (University of Amsterdam, The Netherlands) Deciphering yeast physiology by a multi‐scale framework integrating cell cycle and metabolism Davide Cacchiarelli (TIGEM, Napoli) Understanding transcription factors biology through genomics Adil Mardinoglu (KTH Royal Institute of Technology, Stockholm, Sweden) The employment of systems biology in treatment of liver diseases
  	Poster Prizes and Closing Remarks     [Aula Magna]
  15:00-17:00	Societies' Time SIBV     [Aula Giacomini – Botanica] Elevator Pitch Session Premio Assunta Baccarini Melandri SIMGBM     [Aula Magna] Consegna Premi Franco Tatò e Mario Campa 2018 Assemblea Generale dei Soci

• Posters

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  • Session I
  • Session II

  • Wednesday, 19 September • 13:15-14:30

    Topic 1 - Environmental Microbiology and Biotechnology

    Topic 2 - Genomics, Proteomics and Systems Biology

    Topic 3 - Chromosome Biology, Cell Division and Cell Cycle

    Topic 4 - Transcriptional Mechanisms and Epigenetic Modifications

    Topic 6 - Photosynthesis, Metabolism and Environmental Stress

    Topic 7 - Genetics of Microorganisms

    Topic 8 - DNA Replication, Repair and Recombination

    Topic 9 - Non-coding RNA

    Topic 10 - Plant Nutrition and Biofortification

    Topic 11 - Cellular Stress, Apoptosis and Autophagy

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    P1.1 Khaled Abdelrhman (Florence)
    High similarities in the gut microbiota of the two cetacean species Tursips truncatus and Stenella coerulealba
    
    P1.2 Antonia Bruno (Milan)
    Drinking water microbiota: where biodiversity rules
    
    P1.3 Renata Denaro (Messina)
    Bioremediation in marine environment, opportunities and challenges approaching the Blue Growth
    
    P1.4 Andrea Di Cesare (Genoa)
    Long-term occurrence of antibiotic resistance genes and class 1 integrons in plankton-associated bacteria
    
    P1.5 Luciana Di Gregorio (Monterotondo, RM)
    Biofilms in cooling towers: biodiversity, structure and seasonality
    
    P1.6 Camilla Fagorzi (Sesto Fiorentino, FI)
    Innovation towards sustainable future: new perspectives for bacterial-enhanced phytodepuration
    
    P1.7 Saverio Giampaoli (Rome)
    Clothes from a dead body: the complexity of bacterial populations
    
    P1.8 C. Valeria L. Giosafatto (Naples)
    Bioactive protein-based films containing an antimicrobial apolipoprotein B fragment
    
    P1.9 Amina Habbeche (Annaba, Algeria)
    Production and characterization of keratinase from a newly thermophilic actinvomycete Actinomadura keratinilytica strain Cpt29 isolated from Algeria
    
    P1.10 Giorgia Marcone (Varese)
    Magnetic nanoconjugated teicoplanin: a novel tool for bacterial infection site targeting
    
    P1.11 Elena Montano (Naples)
    Antibacterial and wound healing effects of colloidal silver on human keratinocytes
    
    P1.12 Andreu Paytuví Gallart (Cerdanyola del Vallès, Barcelona, Spain)
    Gaia: integrated metagenomics suite
    
    P1.13 Elisa Piampiano (Florence)
    Screening and selection of Tetraselmis suecica PGP strains
    
    P1.14 Francesco Pini (Florence)
    Dry-fermented salami: evaluating natural products as an alternative to sodium nitrite
    
    P1.15 Mattia Pirolo (Rome)
    Bioluminescence-based biosensor for the detection of the Pseudomonas aeruginosa siderophore pyochelin
    
    P1.16 Daniela Sateriale (Benevento)
    Natural tools in the battle against cariogenic bacteria: in vitro antibacterial effects of polyphenolic extracts of honey and myrtle, also in combination with pomegranate peel extracts, vs S. mutans and R. dentocariosa
    
    P1.17 Emily Schifano (Rome)
    The foodborne strain Lactobacillus fermentum MBC2 triggers pept-1-dependent prolongevity effects in Caenorhabditis elegans
    
    P1.18 Barbara Tonanzi (Monterotondo, RM)
    Anaerobic digestion of food waste: the effect of waste activated sludge addition on microbial population composition
    
    P1.19 Ivano Vigliante (Turin)
    Phytoremediation of whey by Chlorella minutissima induces high lipid accumulation during mixotrophic growth
    
    

    ---

    P2.1 Giulia Babbi (Bologna)
    From diseases and phenotypes to processes and pathways
    
    P2.2 Vincenza Barresi (Catania)
    Transcriptome analysis of zinc homeostasis genes reveals a selective altered expression of zinc transporters in colorectal cancer
    
    P2.3 Luca Brambilla (Milan)
    Glutamate as a multi-purpose nutrient for budding yeast
    
    P2.4 Martina Cristaldi (Catania)
    Isolation and characterization of a primary human corneal epithelial cell line
    
    P2.5 Giovanna De Simone (Rome)
    Nitrobindin: an ubiquitous family of all β-barrel heme-proteins
    
    P2.6 Alessandra Giorgi (Rome)
    The molecular landscape of the amyloid-driven microglia transformation
    
    P2.7 Maria Rosa Mazzoni (Pisa)
    A mouse model of creatine transporter deficiency syndrome: proteomic approach focused on mitochondrial proteins
    
    P2.8 Armando Negri (Milan)
    Post translational modifications of sea urchin toposome induced by environmental factors
    
    P2.9 Graziano Pesole (Bari)
    No Evidence of mtDNA methylation by real-time direct Nanopore sequencing
    
    P2.10 Gabriella Tedeschi (Milan)
    Characterization of the protein corona adsorbed onto novel nanomaterials in biological media
    
    P2.11 David Tómas (Barcelona, Spain)
    AIR: Artificial Intelligence RNAseq
    
    

    ---

    P3.1 Eleonora Cappelletti (Pavia)
    Satellite DNA is responsible for centromere clustering in mammals
    
    P3.2 Fabio Caradonna (Palermo)
    Two immortalized rat astrocyte cell lines as in vitro model for specific cell proliferation studies: cytogenetic and epigenomic characterization and diversification
    
    P3.3 Danilo Cilluffo (Palermo)
    The tumor suppressor p14^ARF hampers proliferation of aneuploid cells induced by CENP-E partial depletion
    
    P3.4 Ilaria Dutto (Barcelona, Spain)
    Identifying new genes linked to cell division and regulation of brain size
    
    P3.5 Jessica Marinaccio (Rome)
    Alternative Lengthening of Telomere (ALT) activated by telomere damage in human primary fibroblasts
    
    P3.6 Arianna Montanari (Rome)
    Yeast Gcn5 histone acetyltransferase is present in the mitoplasts independently from the SAGA complex
    
    P3.7 Federica Polverino (Rome)
    Role of the Aurora-A kinase and its regulator TPX2 in control of spindle orientation in human cells
    
    P3.8 Marilena Taggi (Rome)
    Role of M2 muscarinic receptor in epithelial ovarian carcinoma (EOC)
    
    P3.9 Erika Testa (Rome)
    Degree of X-Y aneuploidy in sperms of mice with altered expression of Spo11 splice variants varies with genetic background
    
    P3.10 Ilaria Virdia (Rome)
    The centrosomal localization of p53 is critical for spindle pole integrity in human nontransformed cells but not in cancer cells
    
    

    ---

    P4.1 Simona Iezzi (Rome)
    Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia
    
    P4.2 Alessandra Egidi (Rome)
    Top1p mediates Fob1p/Sir2p interaction and contributes to rDNA silencing
    
    P4.3 Concetta Federico (Catania)
    3D-FISH and Hi-C to study the organization in the cell nucleus of the 7q36.3 chromosomal region, frequently rearranged in leukemic cells
    
    P4.4 Leonardo Gatticchi (Perugia)
    Ignoring the fats: Tm7sf2 gene disruption impairs in vitro adipocyte differentiation of mouse embryonic fibroblasts
    
    P4.5 Frauke Goeman (Rome)
    Che-1/AATF-induced transcriptionally active chromatin promotes cell growth in Multiple Myeloma
    
    P4.6 Manuela Leo (Rome)
    Ubiquitin protease Ubp8 is necessary for S. cerevisiae respiration
    
    P4.7 Francesco Liguori (Rome)
    Drosophila melanogaster as a model to study in vivo the functional role of Transposable Elements in Huntington’s disease pathogenesis
    
    P4.8 Ernesto Picardi (Bari)
    Genome-wide RNA editing analysis in human neurological disorders
    
    P4.9 Karolina Prajzendanc (Szczecin, Poland)
    Constitutional methylation of BRCA1 gene as breast cancer risk factor
    
    P4.10 Anastasia Ricci (Urbino)
    Dexamethasone effects on HDAC4 in A-T cell lines
    
    

    ---

    P6.1 Cristina Campobenedetto (Turin)
    Salt stress mitigation in lettuce (Lactuca sativa L.) by the application of a new glutamic acid-based biostimulant
    
    P6.2 Alice Capecchi (Perugia)
    A single cystein-enriched phaseolin expressed in transplastomic tobacco plants accumulates as a biopolymer
    
    P6.3 Valentino Casolo (Udine)
    Characterization of calcium uptake in pea stem and root mitochondria
    
    P6.4 Walter Chitarra (Conegliano, TV)
    Leaf responses to water stress of four grapevine varieties grown in the Northern Italy
    
    P6.5 Monica Crociata (Rome)
    Cullin neddylation is regulated by water deprivation in Arabidopsis thaliana
    
    P6.6 Laura De Gara (Rome)
    Redox homeostasis in rice varieties having different sensitivity to salt stress
    
    P6.7 Maria Concetta de Pinto (Bari)
    Nitrogen metabolism at the tillering stage affects grain yield and grain protein content in durum wheat
    
    P6.8 Sergio Esposito (Naples)
    Mediterranean barley (Hordeum vulgare) genotypes as a tool to identify specific roles for HSP70s in response to abiotic stress
    
    P6.9 Graziella Ficociello (Rome)
    The nematode Caenorhabditis elegans to evaluate the effects of some atmospheric particulate matters
    
    P6.10 Amodio Fuggi (Caserta)
    Metabolite distribution during ripening of fruits of sweet cherry landraces of Campania (Italy)
    
    P6.11 Valentina Giacinti (Rome)
    Antioxidant defense systems in cyanobacteria: the extremophile chroococcidiopsis SP. CCME 029 versus the normophyle synechocystis SP. PCC 6803
    
    P6.12 Beatrice Giuntoli (Pisa)
    Development of a synthetic molecular oxygen sensor in plants
    
    P6.13 Antonella Gori (Sesto Fiorentino, FI)
    Ecotype variability in secondary metabolism of Moringa oleifera exposed to severe water deficit and re-watering under high temperature condition
    
    P6.14 Monirul Islam (Turin)
    Effect of geomagnetic field on plant fatty acid content
    
    P6.15 Maura Laus (Foggia)
    Direct measurement of native plant sirtuin activity using a Homogeneous Time-Resolved Fluorescence (HTRF^®)-based assay: first application to durum wheat mitochondria
    
    P6.16 Vittoria Locato (Rome)
    Salt stress responses in rice: focus on the redox control of root growth
    
    P6.17 Claudio Lovisolo (Grugliasco, TO)
    Design and set up of a plant growth chamber for stable isotope labeling to investigate carbon attraction toward fruit sinks and plant reserves upon and after drought stress
    
    P6.18 Cristina Morabito (Grugliasco, TO)
    Apoplastic pH influences grapevine recovery responses to short and prolonged drought
    
    P6.19 Chiara Pagliarani (Turin)
    Transcriptional response of different Vitis vinifera ‘Nebbiolo’ clones involves molecular signals regulating berry development in coordination with stress defence mechanisms
    
    P6.20 Elisa Pellegrini (Udine)
    3D visualization of air-filled tissues in two flood-prone halophytes reveals contrasting bottlenecks for long-distance O₂ transport
    
    P6.21 Francesco Petruzzellis (Trieste)
    A leaf selfie reveals drought resistance: visualizing embolism formation in the venation network using a smartphone
    
    P6.22 Maria Manuela Rigano (Portici, NA)
    Physiological evaluations of tomato cultivars under high temperature stress conditions
    
    P6.23 Francesca Secchi (Grugliasco, TO)
    Micro-CT assisted analysis of xylem recovery from water stress in poplars subjected to chemical inhibition of cellular activity
    
    P6.24 Mario Soccio (Foggia)
    First evidences of the existence of Glyoxalase I activity in durum wheat (Triticum durum Desf.) mitochondria and its activation under hyperosmotic stress conditions
    
    P6.25 Francesca Sparla (Bologna)
    The assembling process of photosynthetic glyceraldehyde-3-phosphate dehydrogenase: the regulation, the structure and something more
    
    P6.26 Roberta Trani (Bari)
    Seasonal changes in Chaetomorpha linum bioremediation capability of acquaculture wastewater
    
    P6.27 Dalila Trupiano (Pesche, IS)
    Tissue-specific hormone profiles from woody poplar roots under bending stress 
    
    

    ---

    P7.1 Giulia Barbieri (Pavia)
    CodY-mediated regulation of gene expression in Group B Streptococcus
    
    P7.2 Michele Bianchi (Rome)
    Connection between hypoxia and glucose regulation in the expression of the glucose transporter gene RAG1 in Kluyveromyces lactis
    
    P7.3 Lara Mitia Castronovo (Sesto Fiorentino, FI)
    Azurin: phylogenetic distribution, possible ecological role and quantification in colorectal cancer (CRC) patients
    
    P7.4 Barbara De Siena (Caserta)
    Characterization of an efflux pump in Mycobacterium smegmatis
    
    P7.5 Sara Del Duca (Sesto Fiorentino, FI)
    Towards microbe-assisted therapy of colon cancer: exploring oral and intestinal human microbiota in patients with CRC
    
    P7.6 Anna Maria Puglia (Palermo)
    Streptomyces coelicolor extracellular vesicles:isolation, purification and characterization
    
    

    ---

    P8.1 Francesca Antonella Aiello (Rome)
    The Werner exonuclease is involved in fork processing and checkpoint activation in response to low-dose of camptothecin
    
    P8.2 Jacopo Albanesi (Rome)
    DNA damage response kinases as a target for the differentiation treatment of acute myeloid leukemia
    
    P8.3 Elisabetta Bassi (Pavia)
    A DDB2 mutated protein, unable to interact with PCNA, affects DNA repair and confers proliferation advantage
    
    P8.4 Francesco Berardinelli (Rome)
    G-quadruplex ligand RHPS4 radiosensitizes glioma xenograft in vivo through a differential targeting of bulky differentiated- and stem-cancer cells
    
    P8.5 Miriana Cardano (Pavia)
    Investigating PCNA acetylation to identify novel biomarkers of DNA replication stress in normal and tumor cells
    
    P8.6 Angela Dello Stritto (Rome)
    TRF1 PARylation by PARP1 is required for the accomplishment of telomere replication
    
    P8.7 Debora Ferri (Pavia)
    XPD mutations differentially affect the cellular composition of TFIIH in XP and TTD patient cells
    
    P8.8 Isabella Guardamagna (Pavia)
    A new functional in vitro "cell-free" assay as a method to study the DNA repair synthesis
    
    P8.9 Giorgia Lillo (Rome)
    Investigating the role of WRNIP1 in response to CPT-induced DNA double strand breaks
    
    P8.10 Eva Malacaria (Rome)
    RAD52 protects replication forks from nascent strand degradation
    
    P8.11 Valeria Maselli (Rome)
    Genotoxic/mutagenic potential of mobile-phone radiofrequency (915 MHz) in human lymphocytes exposed in vitro to continuous or fractional treatments
    
    P8.12 Daniela Muoio (Rome)
    RHPS4 telomeric replication stress in BLM CRISPR/Cas9 knockout glioma cells
    
    P8.13 Valentina Palermo (Rome)
    ATM and CDK1 phosphorylate WRN for a correct and timely execution of DSBs processing
    
    P8.14 Maria Pallotta (Pisa)
    Antioxidant treatment preserves genome stability in SMC1A-mutated Cornelia de Lange syndrome cells
    
    P8.15 Elisa Palumbo (Padua)
    DNA damage repair in Friedreich Ataxia: a novel insight for the comprehension of the pathological phenotype
    
    P8.16 Barbara Pascucci (Rome)
    Post-translational modifications of Drp1 link mitochondrial dysfunction to neurodegenerative features in Cockayne Syndrome A cells
    
    P8.17 Valentina Prota (Rome)
    In vitro evaluation of DNA and chromosomal damage induction by Silver nanoparticles
    
    P8.18 Claudia Scalera (Pavia)
    Nucleotide Excision Repair (NER) XPG endonuclease is induced by loss of p300/CBP acetyl transferase activity and transcription stress
    
    

    ---

    P9.1 Elisa Caffarelli (Rome)
    Neurogenin 2 expression is regulated by the long noncoding RNA HOTAIRM1 during in vitro neuronal differentiation
    
    P9.2 Andrea Carvelli (Rome)
    Noncoding RNA circuitries in motor neuron physiopathology
    
    P9.3 Eleonora D'Ambra (Rome)
    Study of circular RNAs function in murine motor neurons 
    
    P9.4 Michela Denti (Trento)
    microRNA-375 distinguishes neuroendocrine from non-neuroendocrine lung tumors in FFPE samples
    
    P9.5 Fabio Desideri (Rome)
    Charme long noncoding RNA links up with chromatin shaping the 3D nuclear organization
    
    P9.6 Sabrina Garbo (Rome)
    The lncRNA HOTAIR governs epigenetic modifications causal to EMT and is controlled by HNF4a
    
    P9.7 Silvia Gasparini (Rome)
    Neuronal circular RNAs in a mouse model of autism spectrum disorders
    
    P9.8 Aymone Gurtner (Rome)
    Dysregulation of microRNA biogenesis in cancer: the impact of mutant p53
    
    P9.9 Francesca Orso (Turin)
    miR-214 overexpressing mice develop more aggressive mammary gland tumors
    
    P9.10 Ramona Palombo (Rome)
    The pncCCND1_B non-coding RNA assembles a RNA-binding protein complex to regulate cyclin D1 transcription in Ewing sarcoma cells
    
    

    ---

    P10.1 Davide Sega (Verona)
    Determination of magnesium (²⁶Mg) uptake fluxes in grapevine rootstocks through ICP-MS analysis
    
    P10.2 Nicola Tomasi (Udine)
    Implication of copper and iron availability and sources in plant growth and development
    
    P10.3 Laura Zanin (Udine)
    Water-extractable humic substances speed up transcriptional response of maize roots to nitrate
    
    

    ---

    P11.1 Roberto Avola (Catania)
    17b-estradiol regulates mitochondrial metabolism in glioblastoma cells
    
    P11.2 Giuseppina Camiolo (Catania)
    Alpha Lipoic Acid shows antioxidant and chelating properties against the toxic effects induced by iron overload treatment
    
    P11.3 Ilaria Camponeschi (Rome)
    Connections among lipid biosynthesis, ROS metabolism and longevity revealed by the deletion of the hypoxic regulator KlMGA2 in Kluyveromyces lactis
    
    P11.4 Ernestina Capuano (Rome)
    Development of a combination strategy based on ER and oxidative stress in Acute Myeloid Leukemia
    
    P11.5 Francesco Di Meo (Naples)
    Grape seed extracts shows anticancer activity in mesothelioma cell lines
    
    P11.6 Ilaria Genovese (Rome)
    Novel insights on Sorcin (SOluble Resistance-related Calcium binding proteIN)-dependent drug-resistance in H1299 cancer cell line and its molecular binding partners
    
    P11.7 Carla Gentile (Palermo)
    Protective effects of melatonin in inflamed intestinal epithelium are associated with reduced NF-κB activation and changes in DNA methylation status
    
    P11.8 Jie Hyun Kim (Seoul, South Korea)
    Systemic blood pressure alterations contribute to death of retinal ganglion cells in glaucoma
    
    P11.9 Lucia Longhitano (Catania)
    Role of heme oxygenase-1 in uveal melanoma progression
    
    P11.10 Lia Millucci (Siena)
    A comprehensive multisciplinary study on the pathophysiology of the prototype inborn error of metabolism alkaptonuria
    
    P11.11 Fabiana Miraglia (Pisa)
    Elucidation of alpha-synuclein aggregation process by FRET-based biosensors in living cells
    
    P11.12 Luciana Mosca (Rome)
    Polyphenols from Arabidopsis thaliana exert protection against Amyloid beta toxicity
    
    P11.13 Monica Nanni (Rome)
    The aberrant expression of the mesenchymal variant of FGFR2 in the epithelial context inhibits autophagy
    
    P11.14 Daniela Nicolosi (Catania)
    Role of heme oxygenase 1 in glioblastoma cell proliferation and progression
    
    P11.15 Melania Olivieri (Catania)
    Protective effects of 2-fucosyllactose in association with hyaluronic acid against oxidative injury induced by hyperosmolarity 
    
    P11.16 Mauro Patrone (Alessandria)
    Toll-Like Receptors (TRLs): molecular characterization in endothelial cells
    
    P11.17 Maya Petricciuolo (Perugia)
    Is the mitochondrial compartment involved in U118 glioblastoma cell death induced by the antiglycolytic 3-bromopyruvate?
    
    P11.18 Maria Pittalà (Catania)
    Post-translational modifications of voltage dependent anion selective channel (VDAC) isoforms from rat liver mitochondria
    
    P11.19 Elisabetta Rubini (Rome)
    The role of AhR signaling pathways triggered by β-HCH in the progression of prostate cancer
    
    P11.20 Felicia Sangermano (Naples)
    Higginsians: two novel molecules having potential anticancer effects
    
    P11.21 Antonietta Stellavato (Naples)
    Effects of hyaluronic acid based formulation containing amino acids, vitamins, and minerals on oxidative stress using an in vitro cell model of UV-A induced damage
    
    P11.22 Vasile Urechie (Milan)
    Sphingolipid alterations in the cross-talk between primed microglia-and dopaminergic neurons
    
    P11.23 Giulia Vecchiotti (L'Aquila)
    Exposure to particles debris generated from passenger tyres induces genotoxicity and inflammatory response on raw 264.7 cell line
    
    

  • Thursday, 20 September • 13:15-14:30

    Topic 5 - Oncogenes and Tumor Suppressors

    Topic 12 - Development, Differentiation and Ageing

    Topic 13 - Metabolism and its Regulation in Health and Diseases

    Topic 14 - Human Genetics and Genomic Diversity

    Topic 15 - Neurobiology and Neuropharmacology

    Topic 16 - Immunology and Host-Pathogen Interaction

    Topic 17 - Biotransformations

    Topic 18 - Stem Cells, iPS, Cancer Stem Cells

    Topic 19 - Nutrition Biochemistry

    Topic 20 - Evolutionary Biology

    Topic 22 - Plant Development and Disease

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    P5.1 Stefania Carissimi (Rome)
    The natural sesquiterpene β-caryophyllene acts as an enviromental decontaminant through the interference with the STAT3 signalling pathway
    
    P5.2 Daniele Condorelli (Catania)
    Gene expression profiles in genome instabllity-based classes of colorectal cancer
    
    P5.3 Giulia Federici (Rome)
    Can the mitotic centrosomal localization of p53 define ATM variants of uncertain significance (VUS)?
    
    P5.4 Zaira Ianniello (Rome)
    A positive feed-forward regulatory loop between METTL3 and WTAP sustains the oncogenic role of the m6A methylation complex in myeloid leukemia
    
    P5.5 Erica Leonetti (Rome)
    PI3K role in the c-Met-mediated migrating and invading behavior of NT2D1 non-seminoma cells
    
    P5.6 Federica Lo Sardo (Rome)
    In lung cancer, oncogenic YAP/TAZ lead to the inhibition of oncosuppressive TGFBR2 through transcriptional and post-transcriptional mechanisms
    
    P5.7 Roberta Melchionna (Rome)
    hMENA regulates the cross-talk between tumor cells and cancer associated fibroblasts via Gas6/Axl axis
    
    P5.8 Francesco Naso (Rome)
    Role of Aurora-A kinase/TPX2 complex in control of chromosome stability and cell trasformation in human cells
    
    P5.9 Annalisa Pecoraro (Naples)
    Ribosome-free L3 regulates cell proliferation independently of p53 by targeting E2F and inhibiting its function
    
    P5.10 Donatella Ponti (Latina)
    Nucleolar variant of ErbB3 regulates RNA polymerase I activity
    
    P5.11 Ilaria Romito (Rome)
    FAK pharmacological inhibition disrupts hepatocellular carcinoma growth and interferes with liver cancer stem cells markers 
    
    P5.12 Giulia Russo (Naples)
    Role of rpL3 in the translational reprogramming of colon cancer cells resistant to 5-FU
    
    P5.13 Debora Scaldaferri (Varese)
    The pleiotropic roles of the human RNASET2 tumor suppressor gene
    
    P5.14 Giorgia Spampinato (Catania)
    Positive caricature transcriptomic effects associated with broad copy number aberrations in colorectal cancer
    
    

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    P12.1 Walter Arancio (Palermo)
    Progerin expression induces a significant downregulation of transcription from human repetitive sequences in iPSC-derived dopaminergic neurons
    
    P12.2 Maria Arnone (Naples)
    Gene regulatory network approaches for studying the evolution of gut patterning
    
    P12.3 Francesca Bruno (Catania)
    Nucleolar tau protein colocalizes with UBTF and is related to neuronal in vitro differentiation
    
    P12.4 Angela D'Anzi (Rome)
    AHI1gene mutations alter ciliopathy-associated molecular mechanisms in Joubert syndrome
    
    P12.5 Giulia Faravelli (Pavia)
    C. elegans expressing D76N beta-2microglobulin: a useful model for screening drug candidates targeting amyloidosis
    
    P12.6 Chiara Gabellini (Pisa)
    CRISPR/Cas9-induced inactivation of the autism risk gene setd5 leads to social impairments in zebrafish
    
    P12.7 Cristina Giuliani (Bologna)
    Demography and ancient/recent population dynamics shape the genetic architecture of human longevity
    
    P12.8 Manuela Minguzzi (Bologna)
    Effects of Notch1 knockdown on the proliferation and the differentiation of human articular chondrocytes
    
    P12.9 Danilo Ranieri (Rome)
    The keratinocyte differentiation induced by FGFR2b requires sequential involvement of PKCδ and PKCα
    
    

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    P13.1 Cristina Algieri (Ozzano dell'Emilia, BO)
    The inhibition kinetics of the Ca²⁺-activated F-ATPase by F1 inhibitors strengthens its role in the mitochondrial permeability transition pore formation
    
    P13.2 Tiziana Bacchetti (Ancona)
    Role of paraoxonase-2 in chemoresistance in T24 human bladder cancer cells 
    
    P13.3 Francesco Balestri (Pisa)
    The approach of intrasite differential inhibition of aldose reductase in counteracting the onset of diabetic complications and inflammation
    
    P13.4 Matteo Brindisi (Arcavacata di Rende, CS)
    Santolina corsica Jord. & Fourr. extracts exert pro-apoptotic activity and inhibit breast adenocarcinoma cell (MDA-MB-231) migration
    
    P13.5 Alessandra Castegna (Bari)
    Harnessing immunometabolism to fight cancer: lessons from glutamine
    
    P13.6 Angela D'Ascola (Messina)
    Hyaluronan oligosaccharides down-regulate thyroglobulin and NIS expression in human thyrocytes
    
    P13.7 Giulia di Punzio (Parma)
    Saccharomyces cerevisiae as a system to discover beneficial molecules for mitochondrial diseases
    
    P13.8 Mirco Dindo (Perugia)
    Effects of oligomerization on peroxisomal import and stability of human alanine: glyoxylate aminotransferase
    
    P13.9 Monica Emanuelli (Ancona)
    Expression of nicotinamide N-methyltransferase in oral malignant melanoma
    
    P13.10 Luca Frattaruolo (Arcavacata di Rende, CS)
    Elucidating Thioalbamide activity: new insights into TLMs anticancer mechanism
    
    P13.11 Rosanna Gissi (Barletta)
    Histamine catabolism contributes to cardiac injury by sustaining monoamine oxidase-dependent oxidative stress
    
    P13.12 Oh-Shin Kwon (Daegu, South Korea)
    Doxorubicin-induced actin cytoskeleton remodeling was regulated by chronophin activation through RhoA/cofilin signaling in Hela cells
    
    P13.13 Andrea Lia (Lecce)
    A. thaliana enables low-cost, easy and fast in vivo screening of ERQC modulators
    
    P13.14 Andrea Mozzarelli (Parma)
    Differential oxidative stress in a Guinea pig transfusion model causes by high- and low-affinity PEGylated hemoglobin-based oxygen carriers
    
    P13.15 Giulia Murtas (Varese)
    New insights on the modulation of human D-amino acid oxidase
    
    P13.16 Luigi Palese (Bari)
    The protein state of matter: defining a key player in health and disease
    
    P13.17 Anna Pirozzi (Naples)
    In vitro model of hepatic steatosis to test the protective effects of essential oils on lipid accumulation
    
    P13.18 Luciano Piubelli (Varese)
    Are D-serine and D-aspartate serum levels putative biomarkers in Alzheimer’s disease?
    
    P13.19 Elia Ranzato (Vercelli)
    Evaluation of the crosstalk between eIF6-driven translation and mitochondrial metabolism: a multi-approaches definition
    
    P13.20 Agnese Sacchetti (Rome)
    Magnetic resonance spectroscopy-based metabolomic approaches revealed a novel molecular target in metformin treated human glioblastoma cells
    
    P13.21 Pasquale Scarcia (Bari)
    Functional analysis of mitochondrial citrate carrier (SLC25A1) variants linked to combined D-2- and L-2-hydroxyglutaric aciduria
    
    P13.22 Maria Talmon (Novara)
    Bitter taste receptor hTAS2R46 activation regulates mitochondrial Ca²⁺-buffering in airway smooth muscle cells
    
    P13.23 Visith Thongboonkerd (Bangkok, Thailand)
    High glucose induces phosphorylation and oxidation of mitochondrial proteins in renal tubular cells: a proteomics approach
    
    P13.24 Valentina Vassallo (Naples)
    Effects’ study of hyaluronic acid and its hybrid complexes obtained through NAHYCO^TM  technology on an in vitro model of osteoarthritis based on two articular cell types
    
    

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    P14.1 Sofia Beghi (Parma)
    Polymorphism rs7214723 in CAMKK1 and myocardial infarction risk
    
    P14.2 Maria Bonito (Rome)
    Dynamics of gene conversion in human Y-chromosome palindromes
    
    P14.3 Laura Ceccuzzi (Verona)
    Effect of sexual hormones (estradiol and testosterone) on RNASEL and PTGS2 genes expression and miR-146a expression in keratinocyte cells
    
    P14.4 Alda Corrado (Pisa)
    Use of three CRISPR/Cas9-based gene editing systems to study specific alleles within LGALS3 gene
    
    P14.5 Fulvio Cruciani (Rome)
    Rapidly mutating Y-STRs in rapidly expanding populations: discrimination power of the Yfiler Plus multiplex in northern Africa
    
    P14.6 Francesco Donati (Rome)
    Human genetic diversity of drug metabolizing enzymes: implications in doping control tests
    
    P14.7 Nicola Rambaldi Migliore (Pavia)
    Refining the genetic history of Panama through modern and ancient mitogenomes
    
    P14.8 Alessandro Raveane (Pavia)
    The genetic impact of ancient and historical migrations in Southern Italy
    
    P14.9 Bianca Rotoli (Parma)
    Analysis of LPI-triggering mutations of SLC7A7: evidence for defective trafficking and activity
    
    P14.10 Annamaria Buschini (Parma)
    Role of epigenetics in idiopathic male infertility
    
    P14.11 Stefano Sol (Naples)
    Epidermal p63 is essential to control systemic levels of TSLP through repression of Klk6-NFAT signaling
    
    P14.12 Sabrina Turturro (Rome)
    Evaluation of DNA damage in Myotonic dystrophy cells after treatment with different genotoxic agents
    
    

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    P15.1 Valentina Astesana (Pavia)
    Study of the role of calcium on glioma T98G cell line
    
    P15.2 Maria Stefania Brignone (Rome)
    Megalencephalic leukoencephalopathy with subcortical cysts protein-1 (MLC1) controls astrocyte activation in response to inflammatory signals
    
    P15.3 Marina Ceccarini (Rome)
    CRISPR/Cas9-mediated targeted gene correction in MLC patient iPSCs
    
    P15.4 Francesca Cosmi (Rome)
    Hippocampal response to glucocorticoids in Duchenne Muscular Dystrophy: a route to post-traumatic stress disorders?
    
    P15.5 Fabrizio De Luca (Pavia)
    Evaluation of neurotoxic effects of platinum compounds on developing rat cerebellum: inflammatory and oxidative stress pathways
    
    P15.6 Elisa Innocenzi (Rome)
    SLM2 splicing targets are modulated by endocannabinoids in hippocampal neurons
    
    P15.7 Chiara Lico (Rome)
    Plant virus nanoparticles for BBB crossing and drug delivery to medulloblastoma
    
    P15.8 Micaela Lucarelli (Rome)
    BDNF anomalies in Niemann Pick type C disease
    
    P15.9 Alessandro Matera (Rome)
    Expression of acetylcholine nicotinic receptor a7 in rat Schwann cells: implication in nerve regeneration
    
    P15.10 Roberta Piovesana (Rome)
    Cholinergic effects mediated by M2 muscarinic receptor in human Schwann-like cells induced from adipose mesenchymal stem cells
    
    P15.11 Laura Pulze (Varese)
    Altered D-serine levels and neutrophils activation as early markers of inflammation: an in vitro study
    
    P15.12 Silvia Sacchi (Varese)
    Cellular studies on human D-aspartate oxidase
    
    P15.13 Federica Sandrelli (Padua)
    Transcriptional profile of adult dopaminergic neurons in Drosophila melanogaster: a comparison between wild-type and Parkinson’s-related Dj1 mutant flies
    
    P15.14 Ludovica Spagnuolo (Rome)
    New roles for neuroligins/neurexins families during nervous system development
    
    

    ---

    P16.1 Alessandra Aiello (Rome)
    Characterization of the effects induced by the HIV-1 recNEF_SF2 protein on plasmacytoid dendritic cells
    
    P16.2 Tuğba Atabey (Istanbul, Turkey)
    In silico analysis of Omp19 and M24/M37 family peptidase of Brucella abortus to identify the potential T cell epitopes
    
    P16.3 Gianluca Baldanzi (Novara)
    Role of diacylglycerol kinase α in X-linked lymphoproliferative disease and autoimmunity
    
    P16.4 Floriana Cappiello (Rome)
    The frog skin-derived peptides Esc(1-21) and its diastereomer: are they promoters of airway epithelium repair?
    
    P16.5 Duccio Cavalieri (Sesto Fiorentino, FI)
    Saccharomyces cerevisiae induces trained immunity in social wasp queens
    
    P16.6 Lucia Cicchillitti (Rome)
    Circulating biomarkers for tailored treatment strategies in endometrial cancer
    
    P16.7 Eleonora Da Pozzo (Pisa)
    Cytokine secretion responsiveness of lymphomonocytes following cortisol cell exposure: sex differences
    
    P16.8 Marta De Angelis (Rome)
    G6PD deficiency and the redox imbalance: new insights into the susceptibility and the immune response to influenza A virus
    
    P16.9 Cristina Failla (Rome)
    Interleukin (IL)-17/IL-36 axis in the crosstalk between endothelial cells and keratinocytes in inflammatory skin responses
    
    P16.10 Neda Feizi (Rome)
    CD8 T cell responses to apoptosis-associated antigens in Experimental autoimmune encephalomyelitis (EAE), the mouse model of Multiple Sclerosis
    
    P16.11 Stefania Fochi (Verona)
    NF-κB activation mediated by HTLV-1 transactivator Tax protein is impaired in TRAF3 knock-out cells
    
    P16.12 Flavia Giannessi (Rome)
    HIV-1 NEF_sf2 protein increases the exosome production in THP-1 human monocytic cells differentiated with PMA
    
    P16.13 Martina Kunkl (Rome)
    The importance of being Proline: biochemical and functional difference between human and mouse CD28 cytoplasmic tail
    
    P16.14 Laura Mercurio (Rome)
    IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17 treatment
    
    P16.15 Martina Pasqua (Rome)
    Shigella modulation of polyamines during the invasion of host cells
    
    P16.16 Luca Simula (Rome)
    Anti-tumor T cell-mediated immune-surveillance requires the mitochondria pro-fission protein Drp1
    
    P16.17 Alessandro Zennaro (Rome)
    Regulation of Shigella virulence genes expression in response to human gut environment
    
    

    ---

    P17.1 Manuel Benedetti (Verona)
    Development of a microalgal-based powder with thermostable cellulolytic activity
    
    P17.2 Nadia Berterame (Milan)
    Copper homeostasis as a target to improve Saccharomyces cerevisiae tolerance to oxidative stress
    
    P17.3 Loredano Pollegioni (Varese)
    Lignin valorization: a systems biocatalysis approach
    
    P17.4 Raffaele Porta (Naples)
    Milk whey protein-based biomaterials with improved properties
    
    P17.5 Asmaa Sabah/Al-Asmar (Naples)
    Effect of mesoporous silica nanoparticles on the pectin film mechanical properties
    
    

    ---

    P18.1 Tiziana Angrisano (Naples)
    Identification of Prame-target genes as new markers of 2C-like in mouse embryonic stem cells
    
    P18.2 Simona Daniele (Pisa)
    Long lasting inhibition of MDM2-p53 complex potentiates mesenchymal stem cell differentiation into osteoblasts
    
    P18.3 Marco Fiorillo (Salford, United Kingdom)
    Bergamot natural products eradicate cancer stem cells (CSCs) by targeting mevalonate, Rho­GDI­ signalling and mitochondrial metabolism
    
    P18.4 Eugenia Guida (Rome)
    BRafV600E mutation in combination with loss of tumor suppressor Pten in adult NSCs induces astrocytoma formation
    
    

    ---

    P19.1 Sonila Alia (Ancona)
    Taste sensitivity in parkinsonian patients
    
    P19.2 Cristina Angeloni (Camerino)
    Study of the synergistic effects of sulforaphane, epigallocatechin gallate and plumbagin against H₂O₂ in SH-SY5Y cells
    
    P19.3 Maria Teresa Cambria (Catania)
    An in vitro retinoblastoma microvascular endothelial cells model: inhibiting effect of Quercetin and its 8-Methylquercetin Pentamethyl Ether derivative
    
    P19.4 Ivana Caputo (Fisciano, SA)
    The toxic alpha-gliadin peptide 31-43 induces different biological effects in skin-derived cells from celiac subjects and from healthy controls
    
    P19.5 Marco Chiaramonte (Palermo)
    [6]-gingerol effects on the immune system of invertebrates and vertebrates
    
    P19.6 Stefania D'Adamo (Bologna)
    Hydroxytyrosol attenuates the hypomethylation of miR­-9 promoters induced by oxidative stress
    
    P19.7 Guglielmo Duranti (Rome)
    Quercetin supplementation decreases erythrocytes oxidative damage at resting and after an acute bout of eccentric exercise in humans
    
    P19.8 Silvana Hrelia (Rimini)
    Meripillus giganteus extract exerts chemopreventive properties by inducing apoptosis in leukemia cell-lines
    
    P19.9 Giuseppe Mannino (Turin)
    Chemical profile, antioxidant properties and molecular fingerprinting of six varieties of Pistacia vera L.
    
    P19.10 Laura Mazzanti (Ancona)
    Evaluation of dysgeusia in cancer patients: development of effective interventions in future
    
    P19.11 Anna Perrone (Palermo)
    Chemical characterization, molecular fingerprinting and antioxidant activity of leaves of Annona cherimola Mill.
    
    P19.12 Cecilia Prata (Bologna)
    Mechanism underlying the effect of Stevia rebaudiana Bertoni glycosides as insulin-mimetic agents in a Glut-4 -expressing cell model
    
    P19.13 Sara Ragucci (Caserta)
    Primary structure of the myoglobin from Eurasian woodcock (Scolopax rusticola L., family Scolopacidae)
    
    P19.14 Maria Beatrice Ronci (Rome)
    Baobab (Adansonia digitata): a big tree for a “super fruit”. A study about the characterization of bioactive molecules in baobab fruit
    
    P19.15 Guangliang Xing (Nanjing, China)
    Transglutaminase as an effective tool to reduce allergenicity of soy proteins in bio-tofu
    
    

    ---

    P20.1 Marco Barucca (Ancona)
    The evolution of p53 gene family in vertebrates
    
    P20.2 Federica Carducci (Ancona)
    Environmental temperature-related relationship of teleost Rex transposable elements in the phylogenetic analysis
    
    P20.3 Ileana Micarelli (Rome)
    Virtual anthropology in the study of human evolution and history
    
    P20.4 Sara Varano (Rome)
    Feeding people in Medieval Rome: isotope evaluation in several communities of the Roman territory
    
    

    ---

    P22.1 Maria Aragona (Rome)
    Rolb-transformed tomato plants increase their defence response following Pyrenochaeta lycopersici infection
    
    P22.2 Laura Bertini (Viterbo)
    Plant-microbe interaction in Antarctica
    
    P22.3 Matteo Citterico (Rome)
    A Berberine-Bridge enzyme-like protein is a specific oxidase that modifies cellulose oligomers and plays a role in Arabidopsis immunity and development
    
    P22.4 Alessandra Cona (Rome)
    Involvement of Arabidopsis thaliana Copper Amine Oxidase β in maturation of root protoxylem precursors induced by leaf wounding
    
    P22.5 Sara Costantini (Rome)
    SEIPIN proteins affect lipid droplet biogenesis in Arabidopsis to promote pollen transmission and reduce seed dormancy
    
    P22.6 Daniele Del Corpo (Rome)
    Post transcriptional control of AtPME17 expressed in Arabidopsis thaliana during Botrytis cinerea infection
    
    P22.7 Giuseppe Forlani (Ferrara)
    Arabidopsis cultured cells without a functional P5C dehydrogenase show reduced oxidative burst following the exposure to fungal elicitor, but only in the presence of a functional Pro dehydrogenase
    
    P22.8 Ilaria Fraudentali (Rome)
    Involvement of Arabidopsis Copper Amine Oxidase β in MeJA/wounding-induced stomatal closure
    
    P22.9 Roberta Ghelli (Rome)
    The Arabidopsis AUXIN RESPONSE FACTOR 8 (ARF8) controls pollen development by regulating exine pattern formation
    
    P22.10 Moira Giovannoni (Rome)
    Preparing for defense: elicitor-triggered priming of Arabidopsis innate immunity requires AtLYK2 and PCaP1
    
    P22.11 Luca Nerva (Conegliano, TV)
    Unconventional compounds versus endogenous defence mechanisms against powdery mildew: what drives grapevine phyllobiome composition?
    
    P22.12 Emanuela Pedrazzini (Milan)
    UPR engagement during seed storage protein synthesis
    
    P22.13 Silvia Proietti (Viterbo)
    Genome-wide association study REVEALS Novel PLAYERS IN Plant hormone crosstalk
    
    P22.14 Simone Samperna (Rome)
    Characterization of Drechslera gigantea infection in Arabidopsis thaliana and involvement of the unfolded protein response
    
    P22.15 Maria Carmen Valoroso (Naples)
    Analysis of the AP1-, SEP- and AGL6-like genes expressed in the inflorescence of the Mediterranean orchid Orchis italica
    
    P22.16 Ivan Visentin (Grugliasco, TO)
    Strigolactones are involved in the floral induction in tomato
    
    P22.17 Alessandro Vitale (Milan)
    Neofunctionalization of a plant prolamin upon whole genome duplication
    
    P22.18 Michela Zottini (Padua)
    The mitochondrial protein WHIRLY2 is required for efficient functionality of mitochondria during seed development and germination